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Quantitative microbiological risk assessment; new tools to assess and manage risksfrom pathogens in drinking water

机译:定量微生物风险评估;评估和管理饮用水中病原体风险的新工具

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In Canada and other industrialized nations, a combination of guidelines, regulations andgood management practices help ensure that the risk of contracting infectious diseasefrom drinking water is very low. Despite this, outbreaks of waterborne gastroenteritishave occurred, even in the absence of bacteriological indicators. Quantitative microbialrisk assessment (QMRA) tools applied to drinking water offer a risk-based approach tounderstanding how drinking water treatment barriers, and interactions between them, mayimpact human health risk from pathogens.Health Canada and Decisionalysis Risk Consultants Inc. have developed a probabilisticmodel that estimates the level of risk to human health from exposure to index pathogensin treated drinking water. The model explores the impact of water treatment upon theburden of disease associated with pathogens found in drinking water, namelyCryptosporidium parvum, Giardia lamblia, Rotavirus, and pathogenic Escherichia coli.The primary estimates produced by the model are: (i) the reduction in pathogen levels asa result of treatment barriers, (ii) the expected number of illnesses per year from thereference pathogens in treated drinking water, and (iii) the disease burden attributable tothe treated drinking water. To illustrate the use of the tool, data from the City of Ottawais used to estimate the impact of a number of current and future treatment scenarios onthe risk of waterborne disease. Results are used to compare the relative importance ofmultiple treatment barriers during optimal and non-optimal operating conditions. Resultsare also used to determine optimum treatment targets for primary disinfection. TheQMRA model provides a framework for understanding the nature of microbial risk in adrinking water supply system, and can be used to evaluate the impact of changes in watertreatment on population health risk.
机译:在加拿大和其他工业化国家/地区,准则,法规和 良好的管理规范有助于确保感染传染病的风险 喝的水很低。尽管如此,水源性胃肠炎的暴发 即使没有细菌学指标也已发生。定量微生物 用于饮用水的风险评估(QMRA)工具提供了一种基于风险的方法 了解饮用水处理障碍及其之间的相互作用可能如何 影响病原体对人类健康的危害。 加拿大卫生部和Decisionalysis Risk Consultants Inc.已开发出概率 该模型可估算因接触索引病原体而对人体健康造成的风险的水平 在经过处理的饮用水中。该模型探讨了水处理对水处理的影响。 与饮用水中发现的病原体有关的疾病负担,即 小隐孢子虫,兰氏贾第鞭毛虫,轮状病毒和致病性大肠杆菌。 该模型产生的主要估计是:(i)随着病原体水平的降低, 由于治疗障碍,(ii)自 处理过的饮用水中的参考病原体,以及(iii)可归因于该疾病的疾病负担 处理过的饮用水。为了说明该工具的使用,渥太华市的数据 用于估计当前和未来治疗方案对以下方面的影响 水传播疾病的风险。结果用于比较的相对重要性 最佳和非最佳操作条件下的多个处理障碍。结果 还用于确定初次消毒的最佳治疗目标。这 QMRA模型提供了一个框架,可用于了解微生物风险的性质。 饮用水供应系统,可用于评估水变化的影响 人口健康风险的治疗。

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