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Predicting the Ability of Cyclodextrin to Enhance Intestinal Absorption in Controlled Release Delivery: Comparisonwith Immediate Release

机译:预测环糊精在控释释放中增强肠道吸收的能力:与立即释放的比较

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摘要

A model was developed to understand theinfluence of cyclodextrins on oral drug absorption forboth immediate release (IR) and controlled release (CR).Simulation results showed that cyclodextrins enhancedlow solubility drug absorption similarly for IR and CR butdecreased higher solubility drug absorption more for CRthan for IR.
机译:开发了一个模型来了解 环糊精对口服药物吸收的影响 立即释放(IR)和控释(CR)。 模拟结果表明环糊精增强了 与IR和CR相似的低溶解度药物吸收,但 降低较高的溶解度对CR的药物吸收更多 比红外线

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