Self-microemulsifying drug delivery system (SMEDDS) for improved oralbioavailability of mebendazole

摘要

The purpose of the study is to develop a selfmicroemulsifyingdrug delivery system(SMEDDS) for improved bioavailability ofmebendazole, a poorly water soluble drug. Invivo studies in rats demonstrated that theformulation was effective in significantlyenhancing the oral bioavailability of the drug.