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Validation of a Method for Non-invasive Measurement of In Vivo Growth Factor Release from a LocalDelivery System in Bone

机译:从骨局部递送系统无创测量体内生长因子释放的方法的验证

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The therapeutic benefit of local administration ofgrowth factors using a controlled released system forbone regeneration is under study. In this presentwork, a PDGF release profile from chitosan granuleswas obtained using 125I-PDGF as tracer and aprobe-type gamma counter with a collimator. Themeasurement method was validated by theradioactivity values obtained from the isolated boneusing a well-type gamma counter.
机译:局部用药的治疗益处 使用受控释放系统的生长因子 骨再生正在研究中。在这个礼物 壳聚糖颗粒的PDGF释放特性 使用125I-PDGF作为示踪剂和 带有准直仪的探针型伽玛计数器。这 测量方法已通过 从离体骨骼获得的放射性值 使用井型伽玛计数器。

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