Lectin Functionalized Complexation Hydrogels for Oral Protein Delivery

机译：凝集素功能化的复合水凝胶用于口服蛋白质的递送

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Complexation hydrogels were designed to targetdelivery of a protein to the upper small intestine byexploiting the pH shift between the stomach and the uppersmall intestine. pH-sensitive microparticles composed ofmethacrylic acid and poly(ethylene glycol) werefunctionalized with wheat germ agglutinin to deliverinsulin.

机译：络合水凝胶旨在靶向通过以下方式将蛋白质输送到小肠上部利用胃和上肢之间的pH值变化小肠。由pH敏感的微粒组成甲基丙烯酸和聚乙二醇用小麦胚芽凝集素功能化以提供胰岛素。

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《Annual meeting exposition of the Controlled Release Society》|2005年|1-2|共2页
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Kristy M. Wood; Nicholas A. Peppas;
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中图分类药学;
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入库时间 2022-08-26 14:53:50

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1. Wheat Germ Agglutinin Functionalized Complexation Hydrogels for Oral Insulin Delivery [J] . Kristy M.Wood, Gregory M.Stone, Nicholas A.Peppas Biomacromolecules . 2008,第4期

机译：小麦胚芽凝集素功能化复合水凝胶用于口服胰岛素递送
2. pH-responsive and enzymatically-responsive hydrogel microparticles for the oral delivery of therapeutic proteins: Effects of protein size, crosslinking density, and hydrogel degradation on protein delivery [J] . Koetting Michael Clinton, Guido Joseph Frank, Gupta Malvika, Journal of Controlled Release: Official Journal of the Controlled Release Society . 2016,第Null期

机译：pH响应型和酶促响应型水凝胶微粒，用于口服递送治疗性蛋白质：蛋白质大小，交联密度和水凝胶降解对蛋白质递送的影响
3. Complexation hydrogels for oral protein delivery: an in vitro assessment of the insulin transport-enhancing effects following dissolution in simulated digestive fluids [J] . Perakslis E, Tuesca A, Lowman A Journal of biomaterials science . 2007,第12期

机译：用于口服蛋白质递送的复合水凝胶：在模拟消化液中溶解后对胰岛素转运增强作用的体外评估
4. Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Proteins: Evaluation of Protein Release and Bioactivity [C] . Brenda Carrillo-Conde, Stephanie Steichen, Michael C. Koetting, Society for Biomaterials fall symposium 2012.;vol. 34. . 2012

机译：络合水凝胶作为治疗性蛋白质的口服递送载体：蛋白质释放和生物活性的评估
5. Analysis and Novel Characterization of Synthetic and Biologically Enhanced Complexation Hydrogels for Oral Protein Delivery [D] . Marks, F. Michael, III 2011

机译：合成和生物增强的复合水凝胶口服蛋白的分析和新型表征
6. Wheat Germ Agglutinin Functionalized Complexation Hydrogels for Oral Insulin Delivery [O] . Kristy M. Wood, Gregory M. Stone, Nicholas A. Peppas -1

机译：小麦胚芽凝集素功能化复合水凝胶用于口服胰岛素递送
7. Wheat Germ Agglutinin Functionalized Complexation Hydrogels for Oral Insulin Delivery [O] . Kristy M. Wood, Gregory M. Stone, Nicholas A. Peppas 2008

机译：小麦胚芽凝集素官能化络合水凝胶用于口服胰岛素递送

Lectin Functionalized Complexation Hydrogels for Oral Protein Delivery

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