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Constraint Reasoning in Deep Biomedical Models

机译:深度生物医学模型中的约束推理

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Deep biomedical models are often expressed by means of differential equations. Despite their expressive power, they are difficult to reason about and make decisions, given their non-linearity and the important effects that the uncertainty on data may cause. For this reason traditional numerical simulations may only provide a likelihood of the results obtained. In contrast, we propose in this paper the use of a constraint reasoning framework able to make safe decision notwithstanding some degree of uncertainty, and illustrate this approach in the diagnosis of diabetes and the tuning of drug design.
机译:深入的生物医学模型通常通过微分方程表示。尽管它们具有表达能力,但鉴于它们的非线性和数据不确定性可能造成的重要影响,它们仍然难以推理和做出决策。因此,传统的数值模拟可能只能提供获得结果的可能性。相反,我们在本文中提出了使用约束推理框架,尽管存在一定程度的不确定性,该框架仍能够做出安全的决策,并说明了这种方法在糖尿病的诊断和药物设计的调整中的应用。

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