首页> 外文会议>Proceedings of the 29th Annual Meeting of the Controlled Release Society >Effect of Anti-Irritants on the Adverse Dermatological Reaction and Percutaneous Absorption of Captopril Delivery System
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Effect of Anti-Irritants on the Adverse Dermatological Reaction and Percutaneous Absorption of Captopril Delivery System

机译:抗刺激剂对卡托普利输送系统不良皮肤反应和经皮吸收的影响

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摘要

The effect of anti-irritants on the skin irritation inducing by captopril and penetration capability of captopril from gel was investigated. The results showed that diphenhydramine and clobetasol had potent inhibition irritation activity. The experimental formulations possessed appropriate penetration rate and acceptable irritation which could possibly be developed for a transdermal drug delivery system.
机译:研究了抗刺激剂对卡托普利引起的皮肤刺激的作用以及卡托普利从凝胶中的渗透能力。结果表明苯海拉明和氯倍他索具有强大的抑制刺激活性。实验制剂具有合适的渗透速率和可接受的刺激性,这可能会为透皮药物递送系统开发。

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