PREPARATION AND ANTITUMOR EFFECTS OF PIRARUBICIN-ENCAPSULATING LIPOSOMES FOR LIVER CANCER TREATMENT

机译：载有吡柔比星脂质体的脂质体的制备及抗肿瘤作用

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Liver targeted pirarubicin (THP)-entrapping liposomes were prepared and the antitumor effect of the liposomes was evaluated. THP was highly entrapped in liposomes by modified dehydration-rehydration vesicle method. Liposomal THP increased the antitumor effect by decreasing the adverse effects compared with free drug.

机译：制备了靶向肝炎性吡柔比星（THP）的脂质体，并评估了脂质体的抗肿瘤作用。通过改进的脱水-脱水囊泡方法，THP被高度包裹在脂质体中。与游离药物相比，脂质体THP通过减少不良反应来增强抗肿瘤作用。

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《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.535-536|共2页
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Kumi Kawano; Kozo Takayama; Tsuneji Nagai; Gregory Gregoriadis; Yoshie Maitani;
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正文语种
中图分类化学工业;
关键词
liposomes; drug delivery; pirarubicin; surface modification; liver targeting;

机译：脂质体;药物输送;吡柔比星;表面修饰;肝靶向;

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PREPARATION AND ANTITUMOR EFFECTS OF PIRARUBICIN-ENCAPSULATING LIPOSOMES FOR LIVER CANCER TREATMENT

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