首页> 外文会议>AIChE annual meeting >A Tumor (GIST), a Mutated Gene (c-kit), and a Molecular Inhibitor (Imatinib):Insights from Computer Simulations

【24h】

A Tumor (GIST), a Mutated Gene (c-kit), and a Molecular Inhibitor (Imatinib):Insights from Computer Simulations

机译：肿瘤（GIST），突变基因（C-kit）和分子抑制剂（伊马替尼）：计算机模拟见解

获取原文

页面导航

著录项
相似文献
相关主题

著录项

来源
《AIChE annual meeting》|2003年||共6页
会议地点
作者
Sabrina Pricl; Alessandro Coslanich; Maurizio Fermeglia; Marco Ferrone; Veronica Albertini; Loredana Bonadiman; Elena Tamborini; Marco A. Pierotti; Silvana Pilotti;
展开▼
作者单位

展开▼
会议组织
原文格式 PDF
正文语种
中图分类其他化学工业;
关键词

相似文献

外文文献
中文文献
专利

1. The GIST of targeted cancer therapy: a tumor (gastrointestinal stromal tumor), a mutated gene (c-kit), and a molecular inhibitor (STI571). [J] . DeMatteo RP Annals of surgical oncology . 2002,第9期

机译：靶向癌症治疗的GIST：肿瘤（胃肠道间质瘤），突变基因（c-kit）和分子抑制剂（STI571）。
2. Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFR alpha) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs) [J] . Lu Yanli, Mao Fei, Li Xiaokang, Journal of Medicinal Chemistry . 2017,第12期

机译：发现有效，选择性干细胞因子受体/血小板衍生的生长因子受体α（C-KIT / PDGFRα）双抑制剂，用于治疗伊马替尼抗性胃肠肿瘤肿瘤（GIST）
3. Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes. [J] . Burger H, den-Bakker MA, Kros JM, Cancer biology & therapy . 2005,第11期

机译：c-KIT和PDGFRalpha中的激活突变仅在胃肠道间质瘤中发现，而在其他过表达这些甲磺酸伊马替尼靶基因的肿瘤中则没有发现。
4. A Tumor (GIST), a Mutated Gene (c-kit), and a Molecular Inhibitor (Imatinib):Insights from Computer Simulations [C] . Sabrina Pricl, Alessandro Coslanich, Maurizio Fermeglia, AIChE annual meeting . 2003

机译：肿瘤（GIST），突变基因（c-kit）和分子抑制剂（Imatinib）：来自计算机模拟的见解
5. Molecular mechanisms of response in gastrointestinal stromal tumors treated with imatinib mesylate [D] . McAuliffe, John Christopher 2007

机译：甲磺酸伊马替尼治疗胃肠道间质瘤的分子机制
6. Steered Molecular Dynamics Simulations Reveal the Likelier Dissociation Pathway of Imatinib from Its Targeting Kinases c-Kit and Abl [O] . Li-Jun Yang, Jun Zou, Huan-Zhang Xie, 2009

机译：指导的分子动力学模拟从其靶向激酶c-Kit和Abl揭示了伊马替尼的可能解离途径
7. Discovery of Potent Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFR) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs) [O] . -1

机译：发现有效的选择性干细胞因子受体/血小板衍生的生长因子受体α（C-KIT / PDGFR）双抑制剂，用于治疗伊马替尼抗性胃肠肿瘤肿瘤（GISTS）
8. Report on the Relative Efficacy of Oral Cancer Therapy for Medicare Beneficiaries Versus Currently Covered Therapy: Part 2, Imatinib for Gastrointestinal Stromal Tumors (GIST) [R] . Abernethy, A. P., McCrory, D. C. 2005

机译：关于口服癌疗法对医疗保险受益人与目前报道疗法的相对疗效的报告：第2部分，伊马替尼治疗胃肠道间质瘤（GIsT）

A Tumor (GIST), a Mutated Gene (c-kit), and a Molecular Inhibitor (Imatinib):Insights from Computer Simulations

著录项

相似文献

相关主题

期刊订阅