A Strategy for Improving the Yield of Hydrogen by Fermentation

摘要

It was theoretically shown that the yield of hydrogen by fermentation will be improved up to 10 mole of hydrogen from 1 mole of glucose. The maximal yield will be achieved by inhibiting the NADH dehydrogenase complex of the electron transport chain under aerobic condition. Aerobic condition is needed to produce large amount of NADH at TCA cycle and also to re-oxidize FADH2 through electron transport chain by oxygen or other electron acceptors. This method is effective to the facultative anaerobic bacteria or aerobic bacteria with hydrogenase.