Heterogeneity of myocardial fatty acid tracer uptake in the porcine heart wall

摘要

Spatial heterogeneity of myocardial perfusion has been recognized for many years. We have previously shown that whole-body CT is a method for providing the simultaneous measurements of heterogeneity of myocardial perfusion and myocardial blood volume. In the present study we found that the spatial distribution of myocardial metabolism, as indicated by the local accumulation of iodinated phenyl pentadecanoic acid, is slightly more heterogeneous than, but not statistically different from, the heterogeneity of perfusion and blood volume. These findings are consistent with the notion that a common factor is likely to play a major role in determining the spatial heterogeneity of myocardial intravascular blood volume, of myocardial perfusion and of myocardial metabolism.