Cell Tracking and Single Cell Imaging by MRI

摘要

Cellular MRI technology utilizing superparmagnetic iron oxide nanoparticles has progressed quickly over the past decade. Current research is increasingly using clinical MR field strengths, and has demonstrated extremely high detection sensitivity, all the way down to single cell detection in vivo, at both 1.5T and 3T. Our recent work has focused on the optimization of these methods at 3T, and the demonstration of the benefits of 3T over 1.5T for single cell applications such as metastatic cancer cell detection.