Estimation of noise-corrected pulmonary blood flow heterogeneity using positron emission tomography

摘要

The coefficient of variation (CoV) is frequently used to describe functional or structural heterogeneity but is overestimated by the contribution of noise from the measurement method. We evaluated a method to estimate a noise-corrected heterogeneity. It delivers results with a narrow confidence interval. That method has been used to estimate the heterogeneity of pulmonary blood flow in humans as well as in animals.