Measurement of isotopic ratio by tunable diode laser spectroscopy

摘要

Abstract: Although the utility of medical diagnostics based on stable isotope breath tests is well established, the instrumentation available to implement these procedures has been a barrier to their introduction. A tunable diode laser spectrometer for the measurement of isotopic ratios in a clinical setting will be described. The diode laser-based system allows direct measurement without any sample preparation at a cost significantly lower than current techniques. The system design and performance will be presented along with the considerations necessary to allow the instrument to be viable in the clinical environment.!5