Direct fs-laser bacterial inactivation for a biomedical platform

摘要

We demonstrate a total bacterial inactivation technique by ultrashort pulse direct-laser irradiation that does not require any external agent. Near-infrared fs laser pulses at 89 MHz repetition rate were used to irradiate solutions of distilled water with >10~7 cell/ml of wild strain of E. coli, showing they can be inactivated with fluences per pulse as low as ~lmJ/cm~2.