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Daytime Light, Performance and Sleep

机译:日间灯光,表演和睡眠

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摘要

The discovery of intrisically photosensitive, retinal ganglion cells, the photopigment melanopsin and the description of its action spectrum some ten years ago, initiated a rapid development in the field of light and health. Research in animals and humans has shown a surprising similarity in molecular mechanisms and signalling pathways between unicells, amphibians as well as mammmals including humans. These nonvisual light effects contribute to the regulation of e.g. the circadian timing system, sleep-wake, performance, learning, temperature, heart rate and metabolism. The introduction of new light sources is unlikely to worsen the current situation with respect to the nonvisual, eye-mediated, biological effects of light. Rather these new devices will enable light industry, clinical chronobiologists and architects to improve health, save energy and improve learning and performance in large parts of the population. The magnitude of this potential benefit can hardly be overestimated. In order to provide these groups with concrete instructions for application human experimental and applicational studies are desperately needed.
机译:大约十年前,发现本征性光敏性视网膜神经节细胞,光色素黑素和对其作用谱的描述,引发了光与健康领域的快速发展。对动物和人类的研究表明,单细胞,两栖动物以及包括人类在内的哺乳动物之间的分子机制和信号传导途径都具有惊人的相似性。这些非可见光效果有助于例如调节。昼夜节律系统,睡眠-觉醒,表现,学习,温度,心率和新陈代谢。就光的非视觉,眼睛介导的生物效应而言,引入新的光源不太可能使当前状况恶化。相反,这些新设备将使轻工业,临床年代生物学家和建筑师能够改善健康,节省能源并改善大部分人口的学习和绩效。这种潜在利益的规模很难被高估。为了向这些群体提供具体的应用指导,迫切需要进行人类实验和应用研究。

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