Abstract: Temperature increases and the resultant thermal field produced by the irradiation of ex vivo and in vivo tissue models appropriate to the treatment of human breast tissue using Nd:YAG radiation delivered with an interstitial fiber optic probe were recorded with an array of fifteen 23 gauge needle thermocouple probes connected to a laboratory computer based data acquisition system. Using a stepwise decreasing power cycle to avoid tissue charring, acceptably symmetric thermal fields of repeatable volumetric dimensions were obtained. Reproducible thermal gradients and predictable tissue necrosis without carbonization could be induce din a three centimeter diameter region around the fiber probe during a single treatment lasting only 3 minutes. The time-dependence of the temperature rise of the thermocouples surrounding the LITT probe were quantitatively modeled with simple linear functions during the applied laser heating cycles. !14
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