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Theoretical model simulating CO2 laser ablation of biological tissue due to steam pressure generation

机译:模拟由于蒸汽压力产生而对生物组织进行CO2激光消融的理论模型

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Abstract: CO$-2$/ lasers are among the most important lasers used for medical applications such as laser surgery. This laser is used mainly for tissue cutting and tissue removal, exploiting the high power of this laser systems and the high absorption of the biological tissue at this laser wavelength. Our research continues earlier studies conducted at the Tel Aviv University since 1987 that come out with a theoretical model used for simulating tissue irradiated with a CO$-2$/ laser beam. When examining the previous studies on laser ablation we have found that the important mechanism of steam pressure ablation was neglected. Therefore in our work we added steam pressure ablation into the model and studied the effects of this new mechanism on the tissue irradiated with a CO$-2$/ laser. The simulations results reveal that top-hat beam profile (uniformly distributed intensity) produces less thermal damage and its ablation efficiency is higher compared with standard Gaussian beam profile. We saw that the efficiency of the steam pressure ablation process is considerably higher than the purely thermal ablation process. We also noticed that the layers underneath the tissue surface are responsible for the pressure ablation. !18
机译:摘要:CO $ -2 $ /激光器是用于医疗应用(例如激光手术)的最重要的激光器之一。该激光主要用于组织切割和组织切除,它利用了该激光系统的高功率以及在该激光波长下对生物组织的高吸收。我们的研究延续了1987年以来在特拉维夫大学进行的早期研究,得出的理论模型用于模拟用CO $ -2 $ /激光束辐照的组织。在审查先前对激光烧蚀的研究时,我们发现忽略了蒸汽压烧蚀的重要机理。因此,在我们的工作中,我们将蒸汽压力消融添加到模型中,并研究了这种新机制对用CO $ -2 $ /激光辐照的组织的影响。仿真结果表明,与标准高斯光束轮廓相比,礼帽式光束轮廓(强度均匀分布)产生的热损伤较小,其烧蚀效率更高。我们看到,蒸汽压力烧蚀工艺的效率比纯热烧蚀工艺要高得多。我们还注意到组织表面下面的层负责压力消融。 !18

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