Chapter 6 Organic Synthesis in Ionic Liquids Utilizing Organometallic Reagents

摘要

Room temperature ionic liquids (RTILs) have been a focal point of green chemistry and have stimulated interest in both academia and industry for the past several years (1) The physical properties of RTILs offer many advantages. For example, they are non-volatile and thus may be used in high vacuum systems and they are immiscible with a number of organic solvents and thus provide a two phase solvent system. These properties have simplified catalyst recovery in a number of transition metal catalyzed reactions such as Heck reactions (2), ring closing metathesis (RCM) (3), Stille coupling reactions (4), Negishi coupling reaction (5) and Suzuki reactions (6). We have focused our studies on the development of new chemical reactions using these remarkable liquids as solvents in organoboron chemistry.