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Impact of Microdrops on Solid Surfaces for DNA-Synthesis

机译:微滴对固体表面DNA合成的影响

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摘要

The miniaturization of chemical synthesis procedures and their integration in complex microfluidic systems is highly interesting both commercially and scientifically. Here, dosing of microdrops for activation or passivation with high accuracy on a substrate or onto each other is investigated as one approach to gain micron size synthesis spots. To optimize such a system it is necessary to investigate the droplet impact with high temporal and spatial resolution. In this paper we reveal for the first time the impact of microdroplets on solid surfaces in real time. This is done by the visualization of the dynamics with high speed cinematography. Additionally the so gained experimental data is compared to analytical and numerical calculations of this free surface flow.
机译:化学合成方法的小型化及其在复杂的微流体系统中的集成在商业和科学上都是非常有趣的。在此,作为获得微米级合成点的一种方法,研究了在基质上或彼此之间高精度计量激活或钝化微滴的剂量。为了优化这样的系统,有必要以高的时间和空间分辨率研究液滴的冲击。在本文中,我们首次实时揭示了微滴对固体表面的影响。这是通过高速摄影的动态可视化来完成的。另外,将如此获得的实验数据与该自由表面流的分析和数值计算进行比较。

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