Pattern Recognition of Glycyrrhiza uralensis Metabonomics on Rats with MixOmics Package of R Software

摘要

The most widely-used function of Glycyrrhiza uralensis in clinical is regulating property of other drugs, but its mechanism is not explicit. In order to reveal its mechanism, we carried out metabonomics study. The exported LC/MS data were processed by mixOmics package with R.PCA function-including PCA, iPCA and sPCA, PLSDA including valid, and VIP were used to perform pattern recognition.Ability of different functions was evaluated. The results showed PLSDA has powerful discriminative ability of pattern recognition. The mixOmics package is a very useful tool for pattern recognition in metabonomics study.