Natural Polymer-Based Hydrogel Prepared by Graft Co-polymerization of Collagen

摘要

Naturally derived hydrogel forming polymers have frequently been used in tissue engineering applications because they are either components of the natural extracellular matrix (ECM) or have macromolecular properties similar to the ECM. Collagen is the main protein of human tissue and comprise 25% of the total protein mass of most mammals [1,2]. In addition, collagen scaffolds can be created and their mechanical properties enhanced by introducing various chemical crosslinkers. Collagen is