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Single-particle detection using high-refractive index film coated in microring resonator

机译:使用微环谐振器中涂覆的高折射率膜进行单粒子检测

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Detection of the particle especially the nanoparticle attracts much attention in various fields from analysis of various biological materials to environmental monitoring. Microring resonator coated with high refractive index film provides a structure supporting whispering-gallery-modes (WGMs) due to the contrast of the refractive index. This structure can be used as a microfluidic detection and indication of the binding of nanoparticles. In this work, we numerically investigated and optimized this microring resonator, pursuing high quality factors 10~6, yielding the intense light and analyte interactions, as well as extremely high sensitivity and low detection limit. For a single particle adhered to the inner surface of the microring, the eigenmode were investigated. The symmetric and asymmetric modes located the particle at the antinode and node due to the backscattered light coupling between the clockwise and counter-clockwise propagation the WGMs. This leads to the original degenerate resonance mode splitting in frequency. The electric-field intensity distributions along the radius direction near to the film for the fundamental mode and higher order mode were simulated with and without particles. We found that the significant of splitting for the fundamental mode (~ 0.010 THz) due to the scatter of the particles was very different with the separation between fundamental mode and high order mode (~ 1 THz). In addition, the splitting in changed with the size and number of the particle were obtained and the sizes of the particles were estimated which consistent with those in design.
机译:从各种生物材料的分析到环境监测,颗粒尤其是纳米颗粒的检测引起了各个领域的广泛关注。涂覆有高折射率膜的微环谐振器由于折射率的对比而提供了支持耳语画廊模式(WGM)的结构。该结构可以用作微流体检测和纳米颗粒结合的指示。在这项工作中,我们对这种微环谐振器进行了数值研究和优化,以追求10〜6的高质量因子,产生了强烈的光和分析物相互作用,以及极高的灵敏度和低检测限。对于粘附到微环内表面的单个颗粒,研究了本征模。由于WGM顺时针和逆时针传播之间的反向散射光耦合,对称和非对称模式将粒子置于波腹和波腹。这导致原始简并共振模式在频率上分裂。在有或没有粒子的情况下,模拟了基本模式和高阶模式的膜附近沿半径方向的电场强度分布。我们发现,由于粒子的散射,基本模式(〜0.010 THz)的分裂显着性与基本模式和高阶模式(〜1 THz)之间的分离有很大不同。另外,获得了随颗粒尺寸和数量变化的分裂,并估计了颗粒尺寸,这与设计中的一致。

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