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A modified laminar optical tomography system with small dip-angle and the initial validation

机译:改进的具有小倾角的层流光学层析成像系统和初步验证

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摘要

In a typical laminar optical tomography (LOT) system, the dip-angle between the incident light (or the emitting light) and the normal of the detection plane randomly changes during raster-scanning. The inconstant dip-angle causes consistency between the measurement and the light transportation model where a fixed dip-angle of the incident light is generally required. To eliminate the effect from this dip angle, methods such as keeping the angle unchangeable by moving the phantom instead of scanning the light were investigated. In this paper, a LOT system with small dip-angle over the whole detection range is developed. Simulation and experimental evaluation show that the dip-angle of the modified system is much smaller than that of the traditional system. For example, the relative angle between the two incident light at (x=0mm, y=0mm) and (x=0mm, y=2.5mm) on the image plane is about 0.7° for the traditional system while that is only about 0.02° for the modified system. The main parameters of the system are also evaluated and an image reconstruction algorithm is developed based on Monte Carlo simulation. The reconstructed images show that the spatial resolution and quantitative ratio is improved by the modified system without loss of the scanning speed.
机译:在典型的层流光学层析成像(LOT)系统中,在光栅扫描过程中,入射光(或发射光)与检测平面法线之间的倾角随机变化。恒定的倾角会导致测量和光传输模型之间的一致性,在这种情况下,通常需要固定的入射光倾角。为了消除该倾角的影响,研究了诸如通过移动体模而不是扫描光来保持角度不变的方法。本文开发了一种在整个检测范围内具有较小倾角的LOT系统。仿真和实验评估表明,改进后的系统的倾角比传统系统的倾角小得多。例如,对于传统系统,两个入射光在像平面上的(x = 0mm,y = 0mm)和(x = 0mm,y = 2.5mm)处的相对角度约为0.7°,而这仅约为0.02° °用于修改的系统。还评估了系统的主要参数,并基于蒙特卡洛模拟开发了图像重建算法。重建的图像表明,通过改进的系统可以改善空间分辨率和定量比率,而不会降低扫描速度。

著录项

  • 来源
    《Design and quality for biomedical technologies IX》|2016年|97001B.1-97001B.11|共11页
  • 会议地点 San Francisco CA(US)
  • 作者单位

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

    Tianjin Medical University Cancer Institute Hospital, Tianjin, 300102, China;

    Tianjin Medical University Cancer Institute Hospital, Tianjin, 300102, China;

    Tianjin Medical University Cancer Institute Hospital, Tianjin, 300102, China;

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

    College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, 300072, P. R. China;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    laminar optical tomography; pillow distortion correction; spatial resolution; system transfer function; bi-telecentric; image reconstruction;

    机译:层流光学层析成像枕头变形校正;空间分辨率系统传递功能;双远心影像重建;

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