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A Model to Investigate Cell-Surface Interactions: PEGylated Alkanethiolates on Gold –Protein Resistance and Visualization

机译：研究细胞表面相互作用的模型：聚乙二醇化烷硫醇盐对金的蛋白抗性和可视化

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In this study, the resistance of self-assembledmonolayers (SAMs) of PEGylated alkanethiolateswith two different PEG chain lengths on gold tounspecific protein adsorption was investigated bySPR. Furthermore, the development of thesemonolayers was analyzed by Atomic ForceMicroscopy (AFM). After four days, a dense film wasformed and clearly reduced BSA adsorption.

机译：在这项研究中，通过SPR研究了具有两个不同PEG链长的PEG化链烷硫醇盐的自组装单层（SAM）对金的非特异性蛋白吸附的抵抗力。此外，通过原子力显微镜（AFM）分析了这些单层的发展。四天后，形成了致密膜并明显降低了BSA吸附。

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《Controlled Release Society annual meeting》|2004年|1-2|共2页
会议地点 Honolulu, HI(US)
作者
R. Knerr; C. Steinem; C.J. Roberts; A. G?pferich;
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Department of Pharmaceutical Technology University of Regensburg 93040 Regensburg Germanyrobert.knerr@chemie.uni-regensburg.de;

Institut für Analytische Chemie Chemo – und Biosensorik University of Regensburg 93040 Regensburg Germany;

Laboratory of Biophysics and Surface Analysis School of Pharmaceutical Sciences University of Nottingham Nottingham NG7 2RD United Kingdom;

Department of Pharmaceutical Technology University of Regensburg 93040 Regensburg Germany;

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4. A Model to Investigate Cell-Surface Interactions: PEGylated Alkanethiolates on Gold – Protein Resistance and Visualization [C] . Controlled Release Society annual meeting . 2004

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A Model to Investigate Cell-Surface Interactions: PEGylated Alkanethiolates on Gold –Protein Resistance and Visualization

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