RAFT Polymerization, a Versatile Tool for the Production of Functional Soft Nanoparticles

摘要

Block copolymers showing a hydrophilic and a hydrophobic segment were synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization, and their amphiphilic properties were exploited to generate polymeric micelles in water. The hydrophilic corona was subsequently crosslinked covalently to yield surface functional soft nanoparticles showing hydroxyl groups in the case of poly(ethyl acrylate-b-hydroxethyl acrylate) and carboxylic acid groups when using poly(acrylic acid-b-isoprene).