Remote simultaneous dual wavelength imaging photoplethysmography: a further step towards 3-D mapping of skin blood microcirculation

摘要

This paper presents a camera-based imaging photoplethysmographic (PPG) system in the remote detection of PPG signals, which can contribute to construct a 3-D blood pulsation mapping for the assessment of skin blood microcirculation at various vascular depths. Spot measurement and contact sensor have been currently addressed as the primary limitations in the utilization of conventional PPG system. The introduction of the fast digital camera inspires the development of the imaging PPG system to allow ideally non-contact monitoring from a larger field of view and different tissue depths by applying multi-wavelength illumination sources. In the present research, the imaging PPG system has the capability of capturing the PPG waveform at dual wavelengths simultaneously: 660 and 880nm. A selected region of tissue is remotely illuminated by a ring illumination source (RIS) with dual-wavelength resonant cavity light emitting diodes (RCLEDs), and the backscattered photons are captured by a 10-bit CMOS camera at a speed of 21 frames/second for each wavelength. The waveforms from the imaging system exhibit comparable functionality characters with those from the conventional contact PPG sensor in both time domain and frequency domain. The mean amplitude of PPG pulsatile component is extracted from the PPG waveforms for the mapping of blood pulsation in a 3-D format. These results strongly demonstrate the capability of the imaging PPG system in displaying the waveform and the potential in 3-D mapping of blood microcirculation by a non-contact means.