Piecewise Registration for Point-to-Surface Mapping of Cardiac Data

摘要

Patient-specific mapping of point based cardiac data to a segmented heart surface requires accurate point-to-surface registration. The hypothesis is that anatomical movement that occurs between electrophysiological (E-P) data and cardiac image acquisition causes the pulmonary veins to have different orientations relative to the heart. We propose a piecewise registration of the atria and veins to produce a more accurate matching of these data sets. We developed phantoms and simulated clinical data accounting for noise and motion to demonstrate the robustness of the point-to-surface registration algorithm. Then three sets of patient data were used to evaluate rigid and piecewise registration, totaling three left atria and eight pulmonary veins. Analysis using the Student's t-test showed the overall average chamfer distance for the three patients was significantly lower with piecewise registration compared to global rigid registration (p-values = 0.01, 0.05, 0.10). Visual analysis of the global and piecewise registered points confirms the importance of considering the plasticity and locomotion generally inherent in dynamic biological systems when attempting to match data sets acquired from such systems.