The goal of our study is to develop a time-dependent three-compartment model of beacon delivery to simulate the distribution of Indocynanine Green (ICG) in cancer tissue by using JSIM development environment of model simulation and data analysis. We studied the major factors that contribute to distribution of ICG in our model. The simulation results show that our time-dependent three-compartment model can describe the delivery of ICG injected intravenously into the human subject and assist in breast cancer detection.
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