Development of a direct Raman imaging system for rapid diagnosis of malignant tumor

摘要

Raman imaging methods provides visual information of pathological changes of tissues and cells without labeling procedures. We are developing direct Raman imaging technique in order to measure a Raman image of living tissues and cells in a short period without mapping procedure. A preliminary system is prepared consisting of a background-free tunable laser, band-pass filters and a CCD detector. In the present study, it is demonstrated the viability of the technique in a real time measurement of the direct Raman images.