Rapid Infectious Disease Screening for Field Medical Emergencies

摘要

Current blood tests cannot provide rapid support for field medical emergencies that require blood in excess of the tested supply, especially, when additional blood needs to be drawn from the available "walking" pool. A fluorescence-based rapid infectious disease screening system, based on a disposable disk with an array of wash-free, one-step, membrane strips and an array of optical probes can be used to quantify a panel of transmissible diseases in parallel with high specificity, high sensitivity, and operational simplicity. We have designed and constructed a sandwich membrane assay platform and a laboratory prototype optoelectronic measuring device and used this ocmbined system to quantify hepatitis C antibody over the concentraiton range of 2 ng/ml to 100 ng/ml in 3 to 5 minutes.