Rotating wheel filter design and optimization for a uniform depth dose distribution in heavy ion therapy

摘要

Treatment planning of heavy-ion radiotherapy involves predictive calculation of not only the physical dose but also the biological dose in a patient body.The goal in designing beam-modulating devices for heavy ion therapy is to achieve uniform biological effects across the spread-out Bragg peak (SOBP).To achieve this,a mathematical model of Bragg peak movement is presented.The parameters of this model have been resolved with Monte Carlo method.And a rotating wheel filter is designed basing on the velocity of the Bragg peak movement.