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Towards a Characterisation of the Generalised Cladistic Character Compatibility Problem for Non-branching Character Trees

机译:非分支字符树广义广义字符相容性问题的刻画

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In [3,2], the authors introduced the Generalised Cladistic Character Compatibility (GCCC) Problem which generalises a variant of the Perfect Phylogeny Problem in order to model better experiments in molecular biology showing that genes contain information for currently unexpressed traits, e.g., having teeth. In [3], the authors show that this problem is NP-complete and give some special cases which are polynomial. The authors also pose an open case of this problem where each character has only one generalised state, and each character tree is non-branching, a case that models these experiments particularly closely, which we call the Benham-Kannan- Warnow (BKW) Case. In [18], the authors study the complexity of a set of cases of the GCCC Problem for non-branching character trees when the phylogeny tree that is a solution to this compatibility problem is restricted to be either a tree, path or single-branch tree. In particular, they show that if the phylogeny tree must have only one branch, the BKW Case is polynomial-time solvable, by giving a novel algorithm based on PQ-trees used for the consecutive-ones property of binary matrices. In this work, we characterise the complexity of the remainder of the cases considered in [18] for the single-branch tree and the path. We show that some of the open cases are polynomial-time solvable, one by using an algorithm based on directed paths in the character trees similar to the algorithm in [2], and the second by showing that this case can be reduced to a polynomial-time solvable case of [18]. On the other hand, we will show that other open cases are NP-complete using an interesting variation of the ordering problems we study here. In particular, we show that the BKW Case for the path is NP-complete.
机译:在[3,2]中,作者引入了广义克拉德字符兼容性(GCCC)问题,该问题概括了完善系统发育问题的一个变体,以便对分子生物学中的更好实验进行建模,从而表明基因包含有关当前未表达特征的信息,例如牙齿。在[3]中,作者证明了这个问题是NP完全的,并给出了多项式的特殊情况。作者还提出了这个问题的开放案例,其中每个字符只有一个广义状态,并且每个字符树都是非分支的,这种情况特别紧密地模拟了这些实验,我们称其为Benham-Kannan-Warnow(BKW)情况。在[18]中,作者研究了非分支字符树的一组GCCC问题的复杂性,因为解决此兼容性问题的系统树被限制为树,路径或单分支树。尤其是,他们表明,如果系统树必须仅具有一个分支,则通过给出一种基于PQ树的新颖算法(用于二进制矩阵的连续一性),BKW情况就可以多项式时间求解。在这项工作中,我们描述了单分支树和路径在[18]中考虑的其余情况的复杂性。我们显示一些未解决的情况是多项式时间可解的,一种情况是通过使用基于字符树中有向路径的算法,类似于[2]中的算法,第二种情况是通过证明这种情况可以简化为多项式时间可解决的情况[18]。另一方面,使用我们在此研究的排序问题的有趣变体,我们将证明其他未解决的情况都是NP完全的。特别是,我们表明该路径的BKW案例是NP完全的。

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