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Enhancing the imaging performance of electrical capacitance tomography for monitoring osseointegrated prostheses

机译:增强电容层析成像的成像性能,以监测骨整合假体

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摘要

Osseointegrated prostheses (OIP) are an alternative to traditional socket-based prostheses, since amputees can experiencean unrestricted range of motion and improved sensory feedback. However, the risk of infection at the tissue-OIP interfaceis very high. Subcutaneous infections, if undetected at an early stage, can result in prosthesis loosening, bone fracture, andOIP mechanical failure. In order to avoid such issues, most of the current OIP monitoring techniques rely on physicians’inspections and conventional imaging techniques. Recent studies showed that electrical capacitance tomography (ECT),which is inherently noncontact and radiation-free, could potentially be used for imaging OIPs. In addition, embeddedpassive nanocomposites interrogated by ECT could reveal pH changes indicative of infection. However, the ECT imagessuffer from limited resolution. Thus, this study investigated a rotational ECT system in which the ECT electrode array isrotated with respect to its central axis to provide additional electric field interrogation patterns and correspondingmeasurements for solving the ECT inverse problem. The results showed that better quality images could be produced as aresult of the increased number of independent boundary measurements. Furthermore, a limited region tomographyalgorithm was also developed and implemented to image only the region corresponding to the OIP-tissue interface. Bylimiting the region of interest, the ill-posed nature of the ECT inverse problem was significantly reduced, which resultedin enhanced resolution of the reconstructed images. Proof-of-concept was successfully demonstrated through laboratorybasedexperimental tests.
机译:骨集成假体(OIP)是传统基于插座的假体的替代品,因为截肢者可以体验到无限制的活动范围和改善的感觉反馈。但是,在组织-OIP接口处感染的风险很高。如果不能在早期发现皮下感染,可能会导致假体松动,骨折和OIP机械性衰竭。为了避免此类问题,当前大多数OIP监视技术都依赖于医生的检查和常规成像技术。最近的研究表明,固有的非接触式且无辐射的电容层析成像(ECT)可能会用于OIP成像。此外,通过ECT询问的嵌入的\ n \ n \ passive纳米复合材料可以揭示指示感染的pH变化。但是,ECT图像的分辨率有限。因此,本研究研究了一种旋转ECT系统,其中ECT电极阵列相对于其中心轴旋转,以提供附加的电场询问模式和相应的测量方法来解决ECT逆问题。结果表明,由于独立边界测量数量的增加,可以产生质量更好的图像。此外,还开发并实施了有限区域层析成像\算法\算法,以仅对与OIP组织界面相对应的区域成像。通过限制感兴趣的区域,ECT逆问题的不适定性质被大大降低,这导致了重建图像分辨率的提高。概念验证已通过基于实验室的\ r \ n实验测试成功证明。

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  • 会议地点 0277-786X;1996-756X
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    Department of Structural Engineering, University of California-San Diego, La Jolla, CA, 92093,USA;

    Materials Science and Engineering Program, University of California-San Diego, La Jolla, CA,92093, USA;

    Department of Structural Engineering, University of California-San Diego, La Jolla, CA, 92093,USA,Materials Science and Engineering Program, University of California-San Diego, La Jolla, CA,92093, USA kenloh@ucsd.edu;

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