Silver and gold nanoparticles for toxicological research

摘要

The critical issue to introduce the products of nanotechnology is to be safe for the environment and humans. Investigation of the nanoparticle interaction with biological cells is a major task of nanotoxicology. The dependence of the toxicity on the composition of nanomaterial has been studied using the stable aqueous suspension of gold and silver nanoparticles of the same size with narrow distribution function produced by laser ablation of metal target in deionized water using 1062 nm Yb fiber laser with 100 ns pulse duration. The beam was focused on the target surface (fluence 80 J/cm2, spot diameter 40 urn). Investigations have shown that proper preparation of the target surface by given number of scanning cycles allows to produce spherical Ag and Au nanoparticles with required average diameter measured by dynamic light scattering and semi-contact atomic force microscopy (sc-AFM).