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New approaches to the correction of metabolic disorders in experimental diabetes mellitus

机译:校正实验性糖尿病代谢紊乱的新方法

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摘要

In the study the synergism of synthetic organic compound L-14 from a series of substituted 1,3,4-thiadiazines and an endogenous antioxidant ascorbic acid in alloxan diabetes mellitus in rats was established for the first time. It was manifested in the reduction of accumulation of early protein glycation product - fructosamine, effect on free-radical processes and antioxidant protection.
机译:在这项研究中,首次建立了由一系列取代的1,3,4-噻二嗪与内源性抗氧化剂抗坏血酸合成的有机化合物L-14在大鼠四氧嘧啶糖尿病中的协同作用。它表现为减少早期蛋白质糖基化产物-果糖胺的积累,对自由基过程的影响和抗氧化保护。

著录项

  • 来源
  • 会议地点 Yekaterinburg(RU)
  • 作者单位

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Yekaterinburg, Russian Federation;

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Institute of Immunology and Physiology of the Ural Branch of the RAS, Yekaterinburg, Russian Federation;

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Institute of Immunology and Physiology of the Ural Branch of the RAS, Yekaterinburg, Russian Federation;

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Institute of Immunology and Physiology of the Ural Branch of the RAS, Yekaterinburg, Russian Federation;

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Yekaterinburg, Russian Federation;

    Ural Federal University named after the first President of Russia B.N. Yeltsin, Yekaterinburg, Russian Federation;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Diabetes; Compounds; Blood; Proteins; Rats; Protein engineering;

    机译:糖尿病;化合物;血液;蛋白质;鼠类;蛋白质工程;;

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