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Engineering Application Of An Optimization Algorithm Based Modeling And Simulation The Protein Synthesis Process

机译:基于优化算法的蛋白质合成过程建模与仿真的工程应用

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摘要

The processes associated with biological systems are characterized by their high complexity, specificity and efficiency, due to the great variety of mechanisms that participate in them. The process of synthesis of proteins is considered for the cell a key of biological functionality, considering that the protein machinery promotes the great majority of functional processes in biological systems. The central dogma of molecular biology is the mechanism that defines the flow of DNA-RNA-Amino Acids-Proteins gene information, involving the processes of transcription, translation and synthesis. Furthermore, the cell can generate control mechanisms to regulate its own processes in response to intrinsic or extrinsic interactions. Considering the functionality of the processes related to the synthesis and regulation of proteins in biological systems, in this work we developed a genetic algorithm with the potential to optimally solve an engineering problem. The proposed engineering problem is to find the PID controller that has the best performance for the position control of a DC motor. The solution to this problem showed that better results can be obtained with the optimization algorithm proposed in this work than the results obtained from classical tuning techniques.
机译:由于参与其中的机制多种多样,与生物系统相关的过程的特点是其复杂性,特异性和效率高。考虑到蛋白质机制促进了生物系统中的绝大多数功能过程,蛋白质的合成过程被认为是细胞生物学功能的关键。分子生物学的中心教条是定义DNA-RNA-氨基酸-蛋白质基因信息流的机制,涉及转录,翻译和合成过程。此外,细胞可以响应内在或外在相互作用而产生调节其自身过程的控制机制。考虑到与生物系统中蛋白质的合成和调节有关的过程的功能,在这项工作中,我们开发了一种遗传算法,具有最佳解决工程问题的潜力。提出的工程问题是找到对直流电动机的位置控制性能最佳的PID控制器。该问题的解决方案表明,与经典的调整技术相比,使用本文提出的优化算法可以获得更好的结果。

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