Bioreactor for biopharmaceutical production: Simple controlled environment design

摘要

Cell types used to produce therapeutic products are mainly bacterial and mammalian cells. The goal of this design is to maintain controlled environments inside a bioreactor and use it for biopharmaceutical production in bacteria. An ideal bioreactor must contain means of measuring and controlling different parameters that affect the life of bacteria. Available designs for bioreactors are reviewed in order to provide all possible aspects that can be improved in the proposed design. The aim is to design, assemble and build a bioreactor with the optimal parameters via a human-to-machine communication that can support optimal bacterial growth. The bacteria that is proposed to be studied and grown inside of the bioreactor is Escherichia coli, as it is an extremely important model organism in many fields of research which serve as a fundamental tool in medicine.