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Biological characterizations of hyaluronic acid hydrogel particles

机译:透明质酸水凝胶颗粒的生物学特性

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Hyaluronic acid (HA), an anionic polysaccharide, is widely distributed in extracellular matrix of connective tissues. Applications of HA as a drug carrier have been recognized as an important polymer in cell therapy and tissue engineering. Fabrications of nano- or micro- hyaluronic acid particle were performed for its possible application as a drug carrier. HA particles were fabricated by employing untrasonic method. The HA hydrogel particles were evaluated by measuring their swelling and release of model drugs. Its morphological properties were also evaluated by observing with LM and SEM. Biological properties of the HA particles were performed with assays of MTT, BrdU, Neutral red.
机译:透明质酸(HA)是一种阴离子多糖,广泛分布在结缔组织的细胞外基质中。 HA作为药物载体的应用已被认为是细胞疗法和组织工程中的重要聚合物。进行纳米或透明质酸颗粒的制备以用于其可能的药物载体。 HA粒子采用超音速法制备。 HA水凝胶颗粒通过测量模型药物的溶胀和释放来评估。还通过LM和SEM观察来评价其形态学性质。 HA颗粒的生物学特性采用MTT,BrdU,中性红进行测定。

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