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A NUMERICAL STUDY OF WALL SHEAR STRESS OF VISCOUS FLOWS IN CURVED ATHEROSCLEROTIC TUBES

机译:弯曲的动脉粥样硬化管内粘性流壁剪切应力的数值研究

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摘要

Atherosclerosis is a disease of large- and medium-size arteries, which Wolves complex interactions between the artery wall and the blood flow. Both clinical observations and experimental results showed that the fluid shear stress acting on the artery wall plays a significant role in the physical processes which lead to atherosclerosis. Therefore, a sound understanding of the effect of the wall shear stress on atherosclerosis is of practical importance to early detection, prevention and treatment of the disease. A considerable number of studies have been performed to investigate the flow phenomena in human carotid artery bifurcations or curved tubes during the past decades. Numerical studies have supported the experimental results on the correlation between blood flow parameters and atherosclerosis. The objective of this work is to understand the effect of the wall shear stress on atherosclerosis. The mathematical description of pulsatile blood flows is modeled by applying the time-dependent, incompressible Navier-Stokes equations for Newtonian fluids.
机译:动脉粥样硬化是大中型动脉的疾病,它使动脉壁和血流之间的复杂相互作用减弱。临床观察和实验结果均表明,作用于动脉壁上的流体剪切应力在导致动脉粥样硬化的物理过程中起着重要作用。因此,正确认识壁切应力对动脉粥样硬化的影响对疾病的早期发现,预防和治疗具有实际意义。在过去的几十年中,已经进行了大量的研究来研究人颈动脉分叉或弯曲管中的流动现象。数值研究支持了血流参数与动脉粥样硬化之间相关性的实验结果。这项工作的目的是了解壁切应力对动脉粥样硬化的影响。通过对牛顿流体应用时间相关的不可压缩的Navier-Stokes方程,可以对脉动性血流的数学描述进行建模。

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