MODELING TUMOUR CONTROL PROBABILITY IN THE RADIATION THERAPY

摘要

In the paper we present a model which shows that gaps in the radiation therapy of head and neck cancers have dramatic impact on the treatment results measured by tumor control probability (TCP). Our point of view is that the main reason of this effect is doubling of proliferation of cancer cells during treatment gaps. The parameters of the model are found basing on records of 1350 patients with head and neck cancers treated by radiotherapy in the Centre of Oncology in Gliwice during the period between 1980-1989.