Abstract: In this paper we report attempts to directly detect the interaction behavior between erythrocyte and lectin concanavalin a (Con A) as well as phaseolus vulgaris (PHA) on the polystyrene film surface. In the procedure, an optical transducer based reflectance interferometry was set up and used to detect the film thickness change during the lectin adsorption and lectin-erythrocyte interaction. The specific interactions among Con A, PHA and erythrocyte were obtained. The solubility monosaccharide inhibition test confirmed that there is affinity between $alpha@-D-mannose and Con A.!20
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