Drug Resistance and Recent Therapeutic Measures in Controlling of Fascioliasis

摘要

Fascioliasis is a widely distributed disease affecting herbivorous animals.As a result of drug resistance a mixture of two antifasciola drugs (Triclobendazole and Superivomec)was used in trial to overcome this drug resistance.Twenty eight newly weaned white Boskat rabbit aging 1.5 month were divided into 7 groups,six of them were experimentally infected with metacercaria of Fasciola gigantica and one kept as ve control group.Faecal egg count during the clinical course of the disease,counting the worm and its morphological studies and lesion score after postmortem examination were the parameters used to evaluate the effect of different drug mixtures.It had been concluded that the mixture of triclabendazole and superivomec was the mixture of choice.