Improved Modeling of Lane Intensity Profiles on Gel Electrophoresis Images

摘要

The quantitative information extraction from PCR-RFLP gel electrophoresis images requires the efficient modeling of the lane intensity profiles. To improve the acquired modeling accuracy, we introduce two novel ideas that can be incorporated in the modeling process. The first one proposes the use of the simplified integrated Weibull function as the basis function of the employed superposition model and the second proposes switching the domain of the intensity profile to-be-modeled to the unexploited fragment length domain.