SYNERGISTIC FORMULATIONS COMPRISING 3'AZIDO-3'-DEOXYTHYMIDINE AND A GLUCURONIDATION INHIBITOR,A RENAL EXCRETION INHIBITOR OR A NUCLEOSIDE TRANSPORT INHIBITOR

摘要

The invention relates to a method for production of new 3'-azidonucleosides with formula IB, and pharmaceutically acceptable derivatives thereof, IMAGE where C in the formula denotes a purine or pyrimidine base which is bound in the 9 or 1 position, respectively. The compounds are applicable in the treatment and prophylaxis of, in particular, infections caused by Gram- negative bacteria, retrovirus infections, and particularly AIDS.