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NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS

机译:昆虫烟碱乙酰胆碱受体的新型选择性调节剂

摘要

The present invention relates to a compound having the following formula (I): wherein: - A is a (hetero)aryl radical comprising from 5 to 10 carbon atoms, possibly substituted by at least one substituent chosen from the group consisting of: halogen atoms, amino, azido, cyano, nitro, hydroxyl, formyl, carboxyl, amido, (C1-C6)alkyl groups, halo(C1-C6)alkyl groups, (C1-C6)alkoxy groups, alkenyl groups, cycloalkenyl groups, and alkynyl groups, and - R is H, CN or CF3, or their pharmaceutically acceptable salts, racemates, diastereomers or enantiomers.
机译:本发明涉及具有下式(I)的化合物:其中:-A是包含5-10个碳原子的(杂)芳基,其可能被选自以下的至少一个取代基取代:卤素原子,氨基,叠氮基,氰基,硝基,羟基,甲酰基,羧基,酰胺基,(C 1 -C 6 )烷基,卤素(C 1 -C 6 )烷基,(C 1 -C 6 )烷氧基,烯基,环烯基和炔基, -R是H,CN或CF 3 或其药学上可接受的盐,外消旋物,非对映异构体或对映异构体。

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