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NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS

机译:昆虫烟碱乙酰胆碱受体的新选择性调节剂

摘要

The present invention relates to a compound having the following formula (I):wherein:- A is a (hetero)aryl radical comprising from 5 to 10 carbon atoms, possibly substituted by at least one substituent chosen from the group consisting of: halogen atoms, amino, azido, cyano, nitro, hydroxyl, formyl, carboxyl, amido, (C1-C6)alkyl groups, halo(C1-C6)alkyl groups, (C1-C6)alkoxy groups, alkenyl groups, cycloalkenyl groups, and alkynyl groups, and- R is H, CN or CF3,or their pharmaceutically acceptable salts, racemates, diastereomers or enantiomers.
机译:本发明涉及具有下式(I)的化合物:其中: - a是包含5至10个碳原子的(杂)芳基,可能被选自选定的至少一种取代基:卤素原子 ,氨基,氮杂,氰基,硝基,羟基,甲酰基,羧基,氨基,(C1-C6)烷基,卤素(C1-C6)烷基,(C1-C6)烷氧基,链烯基,环烯基和炔基 组,And-R是H,Cn或CF 3,或其药学上可接受的盐,外消旋体,非对映异构体或对映体。

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