Proteinases of the calpain family in water invertebrates and fishes

摘要

Activity of Ca2+-dependent proteinases, or calpains (EC 3.4.22.17), was estimated in a wide range of aquatic invertebrates (Oligochaeta, Hirudinea, Crustacea, Insecta, Gastropoda, Bivalvia) and vertebrates (Osteichthyes). Detected molecular properties of calpains from the tissues of different species allow the con-sideration of the complications of calpain structural organization and regulatory mechanisms in invertebrates and vertebrates from a comparative-evolutionary perspective. Certain conclusions can be drawn about changes in the functional role of this proteolytic system in cell metabolism.