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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Variation of relative transit dose profiles with patient-detector distance.
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Variation of relative transit dose profiles with patient-detector distance.

机译:相对转运剂量分布随患者-检测器距离的变化。

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BACKGROUND AND PURPOSE: In view of using portal images for exit dosimetry, an experimental study is performed of relative transit dose profiles at different distances behind patients (and phantoms) and of their relation to the exit dose profile. MATERIALS AND METHODS: Irregular, homogeneous polystyrene phantoms with a variable thickness to simulate head and neck (H&N) treatments (6-MV photon beam) are investigated by ionization chamber measurements performed close to the exit surface and at various distances behind the phantom (10, 20 and 30 cm). Similar measurements are performed for a rectangular phantom with large inhomogeneities (A1 and air). For one irregular homogeneous phantom and an irregular phantom containing an A1 inhomogeneity, ionization chamber measurements are performed at the exit surface, and a portal film image is taken at 30 cm behind the phantom. Portal films of a patient treated for a head and neck malignancy are evaluated for different air gaps behind the patient. RESULTS: For the irregular phantoms, deviations up to 15% and more are observed between the exit dose profile (along the shaped surface of the phantom) and the transit profile close to the phantom (perpendicular to the beam axis). There is, however, a good agreement--within 3%--between the exit profile and the transit profile at 30 cm. For the rectangular, inhomogeneous phantom, the deviation between the exit profile and the transit dose profile at 30 cm does not exceed 5%; transit dose profiles overestimate the exit dose for the air cavity and underestimate the dose for the A1 inhomogeneity. Measurements on portal films of a H&N patient for different air gaps confirm the order of magnitude of the difference observed between transit dose profiles close to the patient and transit dose profiles at some distance behind the patient. CONCLUSIONS: For 6-MV photon beam treatments with significant thickness variations (H&N), large variations (> 10%) are observed in transit dose profiles as a function of the air gap between the patient and the portal film. For this energy, a good agreement is found between the exit profile and the transit profile at about 30 cm behind the patient.
机译:背景和目的:考虑到使用门户图像进行出口剂量测定,对患者(和体模)后面不同距离处的相对转运剂量曲线及其与出口剂量曲线的关系进行了实验研究。材料与方法:通过电离室测量靠近出口表面并在幻影后面不同距离进行的电离室测量,研究了具有可变厚度的不规则均质聚苯乙烯幻影,以模拟头颈部(H&N)处理(6-MV光子束)。 ,20和30厘米)。对于具有较大不均匀性(A1和空气)的矩形体模,执行了类似的测量。对于一个不规则的均质体模和一个包含A1不均匀性的不规则体模,在出射表面进行电离室测量,并在体模后30 cm处拍摄门膜图像。对患者的头颈部恶性肿瘤的门膜进行评估,以评估患者后方的不同气隙。结果:对于不规则的体模,在出射剂量轮廓(沿体模的成型表面)和靠近体模(垂直于光束轴)的通过轮廓之间观察到高达15%甚至更大的偏差。但是,出口轮廓和过境轮廓在30 cm处达成了很好的协议(在3%以内)。对于矩形,不均匀的体模,在30 cm处出口轮廓和过渡剂量轮廓之间的偏差不超过5%;运输剂量分布图高估了空气出口的剂量,而低估了A1不均匀性的剂量。在H&N患者的门静脉膜上进行不同气隙的测量,可以确认接近患者的转运剂量曲线和距患者一定距离的转运剂量曲线之间观察到的差异的数量级。结论:对于具有明显厚度变化(H&N)的6-MV光子束治疗,在转运剂量曲线中观察到较大的变化(> 10%),这是患者和门脉膜之间气隙的函数。对于这种能量,在离患者大约30 cm处的出口轮廓和运输轮廓之间找到了很好的一致性。

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