We read with great interest the article by Bestas et al entitled "The effect of adrenaline on desflurane-in-duced prolonged QTc interval: a randomized double-blind trial", which is published in the current issue of European Review for Medical and Pharmacological Sciences. The Authors1 investigated the effect of adrenaline on desflurane-induced prolonged corrected QT (QTc) interval. They mentioned that adrenaline prolongs QT interval both in patients with long QT syndrome (LQTS) and in normal patients; and adrenaline QT stress test can be a beneficial tool in detecting LQTS in suspected cases. They concluded that desflurane caused progressive prolongation of the QTc interval, and adrenaline shortened QTc interval at application periods, due to increment in heart rate and ventricular contractility. Although, the current study is well-designed and gives detailed information, some comments may be of interest.
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